hypothyroidism and gout

[jonpayson]

This hypothyroidism and gout discussion is now closed. There is more information on hypothyroidism and gout in the Pseudogout Guidelines.

I have read in various random internet searches that their is a correlation between hypothyroidism and gout…about 15-20% of people with hypothyroidism have gout according to some of the “google search experts”. 

Any truth to that out there?

3 months after i was diagnosed with hypothyroidism and started med for it i got gout, so i’m wondering the validity of this.

Thanks,

JP

[limpy]

I don't know about that but I had Hyperparethyroidisn and had a gland removed. Altho I didn't know I had Gout it at the time of the operation. I had a very sore ankle. Looking back I believe that was one of my first attacks. LIMPY

[jonpayson]

im on 75mcg of levothroxan (not sure on spelling).  I never had any affects of hypothyroidism, just tested low about 6 months ago, and have family hx of it.  my levels are normal now, but the gout started 3 months after I started treatment for it,

JP

[inflammasomed]

High uric acid crystal deposition would lead to both increased hyaluronan (HA) expression and fragmentation and low molecular weight HA fragments bind to toll like receptors (TLR2) and down regulate TSH releasing hormone leading to chronically low or low normal TSH levels with simultaneous low or very low normal T3/T4. I think this would be the cause of Gout-associated hypothyroidism and why replacement therapy might be in order for some.

[trev]

I understood higher levels of |TSH measured were indicative of HypOthyroidism where the body tries to stimulate T3 &T4 production by upping TSH.

Is it the case that high SUA can suppress this mechanism and provide a separate trigger for hypothyroidism?

I see that the new range for TSH in the blood is to be considered 0.3 to3.0 instead of higher. Mine is 2.7 U/mL, which is OK- afaik.

This hypothyroidism and gout discussion is now closed. There is more information on hypothyroidism and gout in the Pseudogout Guidelines. If you need more help, please start a new discussion.

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